Tomofumi Fujino Selected Research

Aarskog Syndrome

1/2010	Proline-rich domain plays a crucial role in extracellular stimuli-responsive translocation of a Cdc42 guanine nucleotide exchange factor, FGD1.
4/2008	Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1.

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Tomofumi Fujino Research Topics

Disease

6	Renal Cell Carcinoma (Grawitz Tumor) 01/2020 - 01/2015
5	Carcinoma (Carcinomatosis) 01/2022 - 01/2015
4	Hepatocellular Carcinoma (Hepatoma) 01/2017 - 12/2012
2	Carcinogenesis 01/2022 - 01/2018
2	Aarskog Syndrome 01/2010 - 04/2008
1	Overactive Urinary Bladder (Overactive Bladder) 01/2022
1	Pain (Aches) 01/2022
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2022
1	Liver Neoplasms (Liver Cancer) 12/2012
1	Leukemia 05/2010
1	Endotoxemia 05/2010
1	Ischemia 03/2009
1	Cholestasis 03/2009
1	Hypoxia (Hypoxemia) 03/2009
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 04/2003
1	Cardiomyopathies (Cardiomyopathy) 04/2003
1	Familial Hypertrophic Cardiomyopathy (Cardiomyopathy, Familial Hypertrophic) 04/2003
1	Glucocorticoid Receptor Deficiency 07/2002

Drug/Important Bio-Agent (IBA)

3	Bile Acids and Salts (Bile Acids)IBA 01/2020 - 03/2009
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 08/2015
2	CholesterolIBA 01/2020 - 01/2017
2	N-(6,7-difluoroquinolonyl)ampicillinIBA 01/2018 - 01/2017
2	Sirtuin 1IBA 01/2018 - 01/2018
2	Messenger RNA (mRNA)IBA 01/2017 - 01/2017
2	Cyclin-Dependent Kinase Inhibitor p16IBA 08/2015 - 12/2012
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 08/2015 - 01/2015
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2010 - 04/2008
2	Serine (L-Serine)FDA Link 01/2010 - 04/2008
2	SKP Cullin F-Box Protein LigasesIBA 01/2010 - 04/2008
2	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 01/2010 - 04/2008
1	CyclinsIBA 01/2022
1	benzamideIBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	icilinIBA 01/2022
1	SaltsIBA 01/2022
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2020
1	Liver X ReceptorsIBA 01/2020
1	Cyclin-Dependent Kinase Inhibitor p21IBA 01/2018
1	LigandsIBA 01/2017
1	CardenolidesIBA 01/2015
1	DigitoxigeninIBA 01/2015
1	GlycosidesIBA 01/2015
1	LipopolysaccharidesIBA 05/2010
1	Biological ProductsIBA 05/2010
1	CarbohydratesIBA 05/2010
1	EndotoxinsIBA 05/2010
1	Peptides (Polypeptides)IBA 05/2010
1	NF-kappa B (NF-kB)IBA 05/2010
1	Isoleucine (L-Isoleucine)FDA Link 01/2010
1	Proline (L-Proline)FDA Link 01/2010
1	Member 11 Subfamily B ATP Binding Cassette TransporterIBA 03/2009
1	p38 Mitogen-Activated Protein KinasesIBA 03/2009
1	beta-Transducin Repeat-Containing ProteinsIBA 04/2008
1	NucleotidesIBA 04/2003
1	phospholambanIBA 04/2003
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 07/2002

Therapy/Procedure

1	Therapeutics 12/2012